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3rd Millennium Receives SBIR Contract from Department of Defense to Develop Innovative Microarray Bioinformatics System
CAMBRIDGE, MA - February 13, 2002 -- 3rd Millennium, a leading bioinformatics consulting firm, announced today that is has received a Phase I Small Business and Innovation and Research (SBIR) contract from the Department of Defense (DOD) to develop an innovative bioinformatics system for the management and analysis of microarray data. This work is supported by the U.S. Army Medical Research and Material Command under Contract No DAMD17-02-C-0040. This proprietary bioinformatics system will advance the DOD's Defense Technology Area Plan in Infectious Diseases of Military Importance by integrating physical lab information with computational information. In developing this bioinformatics platform, 3rd Millennium will utilize certain technologies developed through a $1.8 million Advanced Technology Program (ATP) grant awarded in October 2000 by the U.S. Department of Commerce. Through this SBIR contract, 3rd Millennium will further extend capabilities it has developed in order to significantly advance the management and analysis of microarray data.
Current microarray informatics systems have two fundamental limitations: (1) the biological context of the samples is not recorded, which hinders scientific and statistically relevant queries of the data and (2) computational processes are not tracked, which hampers data analysis. 3rd Millennium's bioinformatics system will address both of these drawbacks by coupling a highly sophisticated Laboratory Information Management System (LIMS) to an Analysis Information Management System (AIMS™) for tracking computational processes-specifically the internal and external analytical information that scientists generate around their physical experiments. The proprietary informatics system will capture not only the physical laboratory processes tied to specific experiments, but also the biological context of the samples used in those processes. This will enable simultaneous querying across both biological context and gene expression criteria.
"As modern biologists we are drowning in a sea of high throughput data. We need systems to enable correlation between disease markers and gene expression as well as systems to record the analytical methods we used to derive those correlations. The bioinformatics system we are developing does both," said Jack Pollard Jr., Ph.D., 3rd Millennium's Principal Investigator on this project.
Richard Dweck, Founder and CEO of 3rd Millennium added, "3rd Millennium's agreement with the DOD further validates one of the most critical issues in informatics: the integration of physical laboratory information with the downstream analysis. We believe integrating this information in a flexible bioinformatics system will allow our clients to achieve greater efficiency within their labs, increase the value they derive from their research initiatives and eventually decrease the time to biological discovery."
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The views, opinions and/or findings contained in this report are those of the author(s) and should not be construed as an official Department of the Army position, policy or decision unless so designated by other documentation.
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